(KAIR)--A 22-year-old mother and her three young children were killed Friday night in a two-vehicle wreck in St. Joseph, Missouri.

KQ-2 TV reports said the crash occurred in the 29-hundred block of Pear Street around 11:00.

Police say two cars crashed head-on sending one of the cars off the road, where it landed upside down in a water-filled ditch.

The mother and two of her children were pronounced dead at the scene.  A third child was taken to the hospital where they later died.

Family members said the children were ages 4, 2 and 1.

Police said two others suffered non-life-threatening injuries in the crash.

The wreck remains under investigation.